The hepatoprotective and antioxidative effect of saffron stigma alcoholic extract against vincristine sulfate induced toxicity in rats
نویسندگان
چکیده
منابع مشابه
The protective effects of saffron stigma alcoholic extract against vincristine sulfate drug-induced renal toxicity in rat
Introduction: Vincristine (VCR) is potential anti-cancer drug that is highly toxic for renal tissue. This study aimed to evaluate the protective effect of alcoholic extract of saffron stigma against vincristine renal toxicity in male rats. Methods: A total number of 50 rats were randomly divided into 10 groups. Different doses of VCR (0.25, 0.5 and 0.75mg/kg) and saffron (0.5 and ...
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15 صفحه اولHepatoprotective effect of Crocus sativus (saffron) petals extract against acetaminophen toxicity in male Wistar rats
Objectives: Acetaminophen (APAP) toxicity is known to be common and potentially fatal. This study aims to investigate the protective effects of hydroalcoholic extract, remaining from Crocus sativus petals (CSP) against APAP-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. Materials and Methods: Wister rats (24) were randomly assigne...
متن کاملHepatoprotective effect of Crocus sativus (saffron) petals extract against acetaminophen toxicity in male Wistar rats
OBJECTIVES Acetaminophen (APAP) toxicity is known to be common and potentially fatal. This study aims to investigate the protective effects of hydroalcoholic extract, remaining from Crocus sativus petals (CSP) against APAP-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. MATERIALS AND METHODS Wister rats (24) were randomly assigne...
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Arnebia euchroma is from Boraginaceae family. Various therapeutic effects have been reported for different species of this plant. The aim of this study was to investigate antioxidant activity of hydroalcoholic extract of the root of A. euchroma and its protective effect on hepatotoxicity induced by CCl4 in mice. In this experimental study, A. euchroma was extracted with ethanol solvent by macer...
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ژورنال
عنوان ژورنال: Interdisciplinary Toxicology
سال: 2019
ISSN: 1337-9569
DOI: 10.2478/intox-2019-0023